Location of Work            Helft lab – Institut Cochin – 22 rue Méchain – 75014 – Paris

Qualifications

Highly motivated candidates with a Ph.D. degree in immunology, cancer biology, or related fields. Must possess good verbal and written communication skills in English. Training and expertise in immunology research, in vivo mouse models or high dimensional technologies will be a plus.

How to apply

Candidates should send a letter containing a statement of interest, curriculum vitae, and names of two references from mentors to [email protected]

The selection process will include an oral presentation and an interview.

Description of lab/research

An ERC-funded post-doctoral fellow position is available in our lab to work on myeloid cells and their role in cancer immunity and immunotherapy.

The focus of the proposed research project is to investigate the role of macrophages in breast cancer immunity. In particular we aim at identifying cells and molecular pathways involved in immunity to tumors using different approaches including patient clinical samples, transgenic mouse models, microscopy and high dimensional technologies (scRNAseq, spatial transcriptomic).

The lab is located within Institut Cochin which offers a rich scientific environment: excellent training for researchers, multi-disciplinary approaches and state-of-the-art facilities.

 Relevant publications from the lab include:

Rodrigo Nalio Ramos, Yoann Missolo-Koussou, Yohan Gerber-Ferder, Christian Bromley, Mattia Bugatti, Nicolas Gonzalo Núñez, Jimena Boari Tosello, Wilfrid Richer, Jordan Denizeau, Christine Sedlik, Pamela Caudana, Fiorella Kotsias, Leticia Laura Niborski, Sophie Viel, Mylène Bohec, Sonia Lameiras, Sylvain Baulande, Laëtitia Lesage, André Nicolas, Didier Meseure, Anne Vincent-Salomon, Fabien Reyal, Charles-Antoine Dutertre, Florent Ginhoux, Lene Vimeux, Emmanuel Donnadieu, Bénédicte Buttard, Jérôme Galon, Santiago Zelenay, William Vermi, Pierre Guermonprez, Eliane Piaggio and Julie Helft. Tissue-resident FOLR2+ macrophages associate with CD8+ T cells infiltration in human breast cancer.

Cell. 2022, March 31;185, 1-19. https://doi.org/10.1016/j.cell.2022.02.021