Jacques NUNES

- Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity. Pierre-Louis Bernard, Rebecca Delconte, Sonia Pastor, Vladimir Laletin, Cathy Costa Da Silva, Armelle Goubard, Emmanuelle Josselin, Rémy Castellano, Adrien Krug, Julien Vernerey, Raynier Devillier, Daniel Olive, Els Verhoeyen, Eric Vivier, Nicholas D Huntington , Jacques A. Nunès #, Geoffrey Guittard # J Immunother Cancer. 2022 May;10(5):e004244. doi: 10.1136/jitc-2021-004244. - Vitamin D controls tumor growth and CD8+ T cell infiltration in breast cancer. Esma Karkeni, Stéphanie O Morin, Berna Bou Tayeh, Armelle Goubard, Emmanuelle Josselin, Rémy Castellano, Cyril Fauriat, Geoffrey Guittard, Daniel Olive, Jacques A Nunès Front Immunol. 2019 Jun 6;10:1307. doi: 10.3389/fimmu.2019.01307. - Modulation of T cell activation in obesity. Stéphanie O Morin, Marjorie Poggi, Marie-Christine Alessi, Jean-Francois Landrier, Jacques A Nunès Antioxid Redox Signal. 2017 Apr 1;26(10):489-500. doi: 10.1089/ars.2016.6746. - Dok1 and Dok2 proteins regulate cell cycle in hematopoietic stem and progenitor cells. Emilie Coppin, Maria De Grandis, Pier Paolo Pandolfi, Marie-Laure Arcangeli, Michel Aurrand- Lions, Jacques A Nunès J Immunol. 2016 May 15;196(10):4110-21. doi: 10.4049/jimmunol.1501037. - Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML). Emilie Coppin, Véronique Gelsi-Boyer, Xavier Morelli, Nathalie Cervera, Anne Murati, Pier Paolo Pandolfi, Daniel Birnbaum, Jacques A Nunès Leukemia. 2015 Feb;29(2):500-2. doi: 10.1038/leu.2014.288. - Dok1 and Dok2 proteins regulate natural killer cell development and function. Javier Celis‐Gutierrez, Marilyn Boyron, Thierry Walzer, Pier Paolo Pandolfi, Stipan Jonjić, Daniel Olive, Marc Dalod, Eric Vivier, Jacques A Nunès EMBO J. 2014 Sep 1;33(17):1928-40. doi: 10.15252/embj.201387404. - ADAPted secretion of cytokines in NK cells. Eric Vivier, Sophie Ugolini, Jacques A Nunès Nat Immunol. 2013 Nov;14(11):1108-10. doi: 10.1038/ni.2737.